STRINGSTRING
mxbD mxbD mxbM mxbM ACS42480.1 ACS42480.1 kdpC kdpC kdpB kdpB ACS42237.1 ACS42237.1 ompR-2 ompR-2 phoB phoB ACS39591.1 ACS39591.1 ompR ompR ACS38670.1 ACS38670.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mxbDTwo-component transcriptional regulator, sensor kinase; Function of homologous gene experimentally demonstrated in an other organism; regulator. (545 aa)    
Predicted Functional Partners:
mxbM
Two-component transcriptional regulator, response regulator; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
 
 0.988
ACS42480.1
Putative PAS sensor hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 
 
0.850
kdpC
Potassium-transporting ATPase KdpC subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
  
  
 0.837
kdpB
Potassium-transporting ATPase ATP-binding subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
  
  
 0.824
ACS42237.1
Putative response regulator receiver; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.822
ompR-2
DNA-binding response regulator in two-component regulatory system with EnvZ; Function of strongly homologous gene; regulator.
 
 0.789
phoB
Phosphate regulon transcriptional regulatory protein PhoB; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
 0.788
ACS39591.1
Hypothetical protein; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
     0.779
ompR
Response regulator in two-component regulatory system (OmpR family); Function of strongly homologous gene; regulator.
 
 
 0.740
ACS38670.1
Putative response regulator receiver; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 
 0.737
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.