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ACS39608.1 ACS39608.1 ACS39607.1 ACS39607.1 ACS39605.1 ACS39605.1 fae-2 fae-2 mch mch mdcC mdcC mtdB mtdB mptG mptG fhcC fhcC fhcD fhcD fhcA fhcA
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query proteins and first shell of interactors
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proteins of unknown 3D structure
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ACS39608.1Orf7. Involved in tetrahydromethanopterin-linked formaldehyde oxidation; Function experimentally demonstrated in the studied strain; putative factor. (289 aa)    
Predicted Functional Partners:
ACS39607.1
Orf5. Involved in biosynthesis of tetrahydromethanopterin. Essential for formaldehyde oxidation; Function experimentally demonstrated in the studied strain; putative enzyme; Belongs to the RimK family.
     0.967
ACS39605.1
Tetrahydromethanopterin C1 transfer protein; Essential for formaldehyde oxidation; Function experimentally demonstrated in the studied strain; putative enzyme.
 
   
 0.881
fae-2
Formaldehyde-activating enzyme; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin, a reaction which also proceeds spontaneously, but at a lower rate than that of the enzyme-catalyzed reaction. Is an essential enzyme for methylotrophic energy metabolism and formaldehyde detoxification of this bacterium.
 
     0.881
mch
N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase (methenyl-H4MPT cyclohydrolase); Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT.
 
     0.879
mdcC
Malonate decarboxylase acyl carrier protein (Malonate decarboxylase delta subunit); Function of strongly homologous gene; enzyme.
  
  
 0.854
mtdB
NAD(P)-dependent methylene tetrahydromethanopterin dehydrogenase; Catalyzes the dehydrogenation of methylene-H(4)MPT.
 
     0.852
mptG
Ribofuranosylaminobenzene 5'-phosphate (RFAP) synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.842
fhcC
Formyltransferase/hydrolase complex Fhc subunit C; Involved in the transformation of 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) and formate via the formylmethanofuran (formyl-MFR).
 
     0.801
fhcD
Formyltransferase/hydrolase complex Fhc subunit D; Involved in the transformation of 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) and formate via the intermediate formylmethanofuran (formyl-MFR). Catalyzes the transfer of a formyl group from 5-formyl-H(4)MPT to MFR so as to produce tetrahydromethanopterin (H(4)MPT) and formyl-MFR, which is then hydrolyzed to formate and MFR; Belongs to the FTR family.
 
     0.798
fhcA
Formyltransferase/hydrolase complex Fhc subunit A; Involved in the transformation of 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) and formate via the formylmethanofuran (formyl-MFR). May be catalyze the hydrolysis of formylmethanofuran (formyl-MFR) to yield formate and MFR. Belongs to the metallo-dependent hydrolases superfamily. FwdA/FmdA family.
 
     0.798
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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