node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38130.1 | ACS39663.1 | MexAM1_META1p0167 | MexAM1_META1p1821 | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.498 |
ACS38130.1 | ACS39682.1 | MexAM1_META1p0167 | MexAM1_META1p1840 | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.937 |
ACS38130.1 | clpA | MexAM1_META1p0167 | MexAM1_META1p5259 | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | 0.945 |
ACS38130.1 | clpB | MexAM1_META1p0167 | MexAM1_META1p2349 | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.945 |
ACS38130.1 | grpE | MexAM1_META1p0167 | MexAM1_META1p0230 | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | Putative heat shock protein (HSP-70 COFACTOR), grpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction c [...] | 0.962 |
ACS38130.1 | hrcA | MexAM1_META1p0167 | MexAM1_META1p0314 | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.865 |
ACS38130.1 | htpG | MexAM1_META1p0167 | MexAM1_META1p0793 | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | Chaperone Hsp90, heat shock protein C 62.5; Molecular chaperone. Has ATPase activity. | 0.973 |
ACS39663.1 | ACS38130.1 | MexAM1_META1p1821 | MexAM1_META1p0167 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | 0.498 |
ACS39663.1 | ACS39682.1 | MexAM1_META1p1821 | MexAM1_META1p1840 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.741 |
ACS39663.1 | clpA | MexAM1_META1p1821 | MexAM1_META1p5259 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | 0.428 |
ACS39663.1 | clpB | MexAM1_META1p1821 | MexAM1_META1p2349 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.428 |
ACS39663.1 | dnaK | MexAM1_META1p1821 | MexAM1_META1p3164 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.498 |
ACS39663.1 | fdh1B | MexAM1_META1p1821 | MexAM1_META1p5031 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Tungsten-containing formate dehydrogenase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.971 |
ACS39663.1 | htpG | MexAM1_META1p1821 | MexAM1_META1p0793 | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Chaperone Hsp90, heat shock protein C 62.5; Molecular chaperone. Has ATPase activity. | 0.575 |
ACS39682.1 | ACS38130.1 | MexAM1_META1p1840 | MexAM1_META1p0167 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Molecular chaperone, HSP70 class; Function of strongly homologous gene; factor. | 0.937 |
ACS39682.1 | ACS39663.1 | MexAM1_META1p1840 | MexAM1_META1p1821 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.741 |
ACS39682.1 | clpA | MexAM1_META1p1840 | MexAM1_META1p5259 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. | 0.716 |
ACS39682.1 | clpB | MexAM1_META1p1840 | MexAM1_META1p2349 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Protein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.716 |
ACS39682.1 | dnaK | MexAM1_META1p1840 | MexAM1_META1p3164 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.937 |
ACS39682.1 | fdh1B | MexAM1_META1p1840 | MexAM1_META1p5031 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Tungsten-containing formate dehydrogenase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.724 |