STRINGSTRING
hom hom asdB asdB metX metX thrC thrC metAS metAS ask ask dapA dapA metH metH thrB thrB ACS38462.1 ACS38462.1 ACS41315.1 ACS41315.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
homHomoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (440 aa)    
Predicted Functional Partners:
asdB
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 0.975
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 0.971
thrC
Threonine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.960
metAS
Putative homoserine O-succinyltransferase (metA); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
  
 
 0.959
ask
Aspartate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family.
 
 0.953
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.953
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.949
thrB
Homoserine kinase; Function of strongly homologous gene; enzyme; Belongs to the pseudomonas-type ThrB family.
 
  
 0.949
ACS38462.1
Putative dihydrodipicolinate synthase (dapA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DapA family.
 
 
 0.940
ACS41315.1
Putative homoserine O-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the AB hydrolase superfamily. MetX family.
 
 
 0.935
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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