STRINGSTRING
ACS39850.1 ACS39850.1 dnaN dnaN ACS39849.1 ACS39849.1 rpmE rpmE recF recF rpmJ rpmJ dnaB dnaB ribE-2 ribE-2 recO recO ACS38289.1 ACS38289.1 ppk ppk
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ACS39850.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (252 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.971
ACS39849.1
Putative permease (PerM family); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
    0.918
rpmE
50S ribosomal protein L31; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bL31 family.
 
    0.824
recF
Putative RecF protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
 
  
 0.814
rpmJ
50S ribosomal protein L36; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bL36 family.
  
    0.796
dnaB
Replicative DNA helicase (dnaB); Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
 
 
 
 0.772
ribE-2
Riboflavin synthase, alpha subunit; Function of strongly homologous gene; enzyme.
   
    0.739
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.730
ACS38289.1
Conserved hypothetical protein precursor; Homologs of previously reported genes of unknown function.
  
     0.626
ppk
Polyphosphate kinase, component of RNA degradosome; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
     
 0.623
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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