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uppS uppS cdsA cdsA ispA ispA dxr dxr ispB ispB crtE crtE frr frr bacA bacA ACS41198.1 ACS41198.1 uppS-2 uppS-2 ACS39868.1 ACS39868.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
uppSUndecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (259 aa)    
Predicted Functional Partners:
cdsA
CDP-diglyceride synthase; Function of strongly homologous gene; enzyme; Belongs to the CDS family.
 
  
 0.971
ispA
Geranyltranstransferase (farnesyl-diphosphate synthase); Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
 
 
 0.965
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.963
ispB
Octaprenyl diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
 
 
 0.956
crtE
Geranylgeranyl pyrophosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
 
 
 0.954
frr
Ribosome recycling factor (Ribosome releasing factor) (RRF); Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
  
 0.925
bacA
Undecaprenyl-diphosphatase (Undecaprenyl pyrophosphate phosphatase) (Bacitracin resistance protein); Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
     
 0.920
ACS41198.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.908
uppS-2
Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 
0.907
ACS39868.1
Membrane-associated zinc metalloprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.898
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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