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amtB amtB glnK glnK glnB glnB glnL glnL cysG cysG gltB gltB bchL bchL cynS cynS acnA acnA glnII glnII glnG-2 glnG-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
amtBAmmonium transport protein (Amt family); Function of strongly homologous gene; transporter. (498 aa)    
Predicted Functional Partners:
glnK
Nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.
 
 0.998
glnB
Regulatory protein (P-II) for nitrogen assimilation by glutamine synthetase (ATase); Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.
 
 0.997
glnL
Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL; Function of strongly homologous gene; enzyme.
  
 
 0.830
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
     
 0.799
gltB
Glutamate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.788
bchL
Protochlorophyllide reductase iron-sulfur ATP-binding protein BchL; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
  
  
 0.754
cynS
Cyanate lyase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family.
      
 0.689
acnA
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.669
glnII
Glutamine synthetase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.661
glnG-2
Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator.
   
  
 0.661
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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