STRINGSTRING
radC radC ACS38159.1 ACS38159.1 ACS40570.1 ACS40570.1 ACS39244.1 ACS39244.1 map-2 map-2 ACS42735.1 ACS42735.1 mutL mutL hyi hyi mutS mutS dprA dprA ACS38806.1 ACS38806.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radCDNA repair protein RadC; Function of strongly homologous gene; cell process; Belongs to the UPF0758 family. (248 aa)    
Predicted Functional Partners:
ACS38159.1
Putative phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
    0.873
ACS40570.1
Putative septum formation protein, Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
  
 0.868
ACS39244.1
Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.844
map-2
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
       0.768
ACS42735.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
 
  
 0.760
mutL
DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.759
hyi
Hydroxypyruvate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the hyi family.
      
 0.747
mutS
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.737
dprA
DNA protecting protein DprA; Function of strongly homologous gene; factor.
  
  
 0.716
ACS38806.1
Putative Cellulose synthase catalytic subunit (UDP-forming); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.644
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.