node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39281.1 | cysD | MexAM1_META1p1419 | MexAM1_META1p2229 | 3'(2'), 5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.958 |
ACS39281.1 | cysG | MexAM1_META1p1419 | MexAM1_META1p3434 | 3'(2'), 5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.513 |
ACS39281.1 | cysH | MexAM1_META1p1419 | MexAM1_META1p2230 | 3'(2'), 5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.934 |
ACS39281.1 | cysN | MexAM1_META1p1419 | MexAM1_META1p2228 | 3'(2'), 5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.943 |
ACS42546.1 | ACS42547.1 | MexAM1_META1p4939 | MexAM1_META1p4940 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative ferredoxin--nitrite reductase (nirA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.989 |
ACS42546.1 | cysD | MexAM1_META1p4939 | MexAM1_META1p2229 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.771 |
ACS42546.1 | cysG | MexAM1_META1p4939 | MexAM1_META1p3434 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.910 |
ACS42546.1 | cysH | MexAM1_META1p4939 | MexAM1_META1p2230 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.979 |
ACS42546.1 | cysI | MexAM1_META1p4939 | MexAM1_META1p2233 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.997 |
ACS42546.1 | cysJ | MexAM1_META1p4939 | MexAM1_META1p2232 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Sulfite reductase, alpha subunit (flavoprotein); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.929 |
ACS42546.1 | cysN | MexAM1_META1p4939 | MexAM1_META1p2228 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.873 |
ACS42546.1 | sseA | MexAM1_META1p4939 | MexAM1_META1p2537 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-mercaptopyruvate sulfurtransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.923 |
ACS42546.1 | ssuE | MexAM1_META1p4939 | MexAM1_META1p3632 | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | NAD(P)H-dependent FMN reductase; Function of strongly homologous gene; enzyme. | 0.906 |
ACS42547.1 | ACS42546.1 | MexAM1_META1p4940 | MexAM1_META1p4939 | Putative ferredoxin--nitrite reductase (nirA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.989 |
ACS42547.1 | cysD | MexAM1_META1p4940 | MexAM1_META1p2229 | Putative ferredoxin--nitrite reductase (nirA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.846 |
ACS42547.1 | cysG | MexAM1_META1p4940 | MexAM1_META1p3434 | Putative ferredoxin--nitrite reductase (nirA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.966 |
ACS42547.1 | cysH | MexAM1_META1p4940 | MexAM1_META1p2230 | Putative ferredoxin--nitrite reductase (nirA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. | 0.965 |
ACS42547.1 | cysJ | MexAM1_META1p4940 | MexAM1_META1p2232 | Putative ferredoxin--nitrite reductase (nirA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | Sulfite reductase, alpha subunit (flavoprotein); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. | 0.923 |
ACS42547.1 | cysN | MexAM1_META1p4940 | MexAM1_META1p2228 | Putative ferredoxin--nitrite reductase (nirA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.848 |
cysD | ACS39281.1 | MexAM1_META1p2229 | MexAM1_META1p1419 | Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 3'(2'), 5'-bisphosphate nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.958 |