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cysJ cysJ cysI cysI cysH cysH cysK cysK cysK-2 cysK-2 cysD cysD nasA nasA cysN cysN ACS42546.1 ACS42546.1 sseA sseA ACS42547.1 ACS42547.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cysJSulfite reductase, alpha subunit (flavoprotein); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (591 aa)    
Predicted Functional Partners:
cysI
Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 0.999
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite.
 
 
 0.996
cysK
Subunit of cysteine synthase A and O-acetylserine sulfhydrolase A, PLP-dependent enzyme; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.978
cysK-2
Cysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.978
cysD
Sulfate adenylyltransferase subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.956
nasA
Nitrate reductase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
  
 0.938
cysN
ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.930
ACS42546.1
Putative sulfite reductase (NADPH); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 
0.929
sseA
3-mercaptopyruvate sulfurtransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.923
ACS42547.1
Putative ferredoxin--nitrite reductase (nirA-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.923
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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