node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39868.1 | ACS40059.1 | MexAM1_META1p2067 | MexAM1_META1p2273 | Membrane-associated zinc metalloprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | 0.773 |
ACS39868.1 | oxaA | MexAM1_META1p2067 | MexAM1_META1p2354 | Membrane-associated zinc metalloprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Transmembrane protein, OxaA-like, preprotein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.434 |
ACS39868.1 | rnhB | MexAM1_META1p2067 | MexAM1_META1p1723 | Membrane-associated zinc metalloprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | RNAse HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.407 |
ACS40059.1 | ACS39868.1 | MexAM1_META1p2273 | MexAM1_META1p2067 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Membrane-associated zinc metalloprotease; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.773 |
ACS40059.1 | bamD | MexAM1_META1p2273 | MexAM1_META1p3156 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.744 |
ACS40059.1 | lepA | MexAM1_META1p2273 | MexAM1_META1p1025 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.837 |
ACS40059.1 | minE | MexAM1_META1p2273 | MexAM1_META1p1054 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.787 |
ACS40059.1 | oxaA | MexAM1_META1p2273 | MexAM1_META1p2354 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Transmembrane protein, OxaA-like, preprotein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.810 |
ACS40059.1 | rnc | MexAM1_META1p2273 | MexAM1_META1p2274 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.961 |
ACS40059.1 | rnhB | MexAM1_META1p2273 | MexAM1_META1p1723 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | RNAse HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.845 |
ACS40059.1 | rpmF | MexAM1_META1p2273 | MexAM1_META1p3696 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | 50S ribosomal subunit protein L32; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL32 family. | 0.685 |
ACS40059.1 | rpoN | MexAM1_META1p2273 | MexAM1_META1p2466 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Sigma N (sigma 54) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.698 |
ACS40059.1 | yliG | MexAM1_META1p2273 | MexAM1_META1p4287 | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Putative AdoMet-dependent methyltransferase, UPF0004 family; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.776 |
bamD | ACS40059.1 | MexAM1_META1p3156 | MexAM1_META1p2273 | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | 0.744 |
bamD | minE | MexAM1_META1p3156 | MexAM1_META1p1054 | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.605 |
bamD | oxaA | MexAM1_META1p3156 | MexAM1_META1p2354 | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Transmembrane protein, OxaA-like, preprotein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.710 |
bamD | rpoN | MexAM1_META1p3156 | MexAM1_META1p2466 | Putative lipoprotein UPF0169; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Sigma N (sigma 54) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.510 |
lepA | ACS40059.1 | MexAM1_META1p1025 | MexAM1_META1p2273 | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Signal peptidase I (SPase I) (leader peptidase I); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | 0.837 |
lepA | rnc | MexAM1_META1p1025 | MexAM1_META1p2274 | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.437 |
lepA | rpmF | MexAM1_META1p1025 | MexAM1_META1p3696 | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 50S ribosomal subunit protein L32; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL32 family. | 0.843 |