STRINGSTRING
rlmH rlmH rsfS rsfS nadD nadD ACS40072.1 ACS40072.1 ACS40073.1 ACS40073.1 prmA prmA yhhF yhhF engB engB ACS40071.1 ACS40071.1 yraL yraL queE queE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
rlmHConserved hypothetical protein, UPF0247 protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (165 aa)    
Predicted Functional Partners:
rsfS
Conserved hypothetical protein, Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
  
 0.890
nadD
Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.836
ACS40072.1
Putative periplasmic carboxyl-terminal processing protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S41A family.
       0.800
ACS40073.1
Putative membrane-bound metallopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.800
prmA
Ribosomal protein L11 methyltransferase (L11 Mtase); Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family.
 
   
 0.635
yhhF
Putative methyltransferase with SAM-dependent methyltransferase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.620
engB
Putative GTP-binding protein engB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
 
  
 0.594
ACS40071.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.558
yraL
Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
   
 0.555
queE
Conserved hypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
   
    0.552
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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