node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39340.1 | ACS40088.1 | MexAM1_META1p1478 | MexAM1_META1p2304 | Putative DNA polymerase III, delta subunit, holA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.451 |
ACS39340.1 | polA | MexAM1_META1p1478 | MexAM1_META1p2436 | Putative DNA polymerase III, delta subunit, holA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.539 |
ACS40087.1 | ACS40088.1 | MexAM1_META1p2303 | MexAM1_META1p2304 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.533 |
ACS40088.1 | ACS39340.1 | MexAM1_META1p2304 | MexAM1_META1p1478 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | Putative DNA polymerase III, delta subunit, holA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.451 |
ACS40088.1 | ACS40087.1 | MexAM1_META1p2304 | MexAM1_META1p2303 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.533 |
ACS40088.1 | ACS42111.1 | MexAM1_META1p2304 | MexAM1_META1p4480 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | Putative flagellar assembly protein FliH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; structure. | 0.446 |
ACS40088.1 | osmC | MexAM1_META1p2304 | MexAM1_META1p2305 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | Osmotically inducible protein OsmC; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.545 |
ACS40088.1 | polA | MexAM1_META1p2304 | MexAM1_META1p2436 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.512 |
ACS40088.1 | radA | MexAM1_META1p2304 | MexAM1_META1p4318 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.873 |
ACS40088.1 | recA | MexAM1_META1p2304 | MexAM1_META1p2721 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.909 |
ACS40088.1 | recN | MexAM1_META1p2304 | MexAM1_META1p3158 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.520 |
ACS40088.1 | ruvC | MexAM1_META1p2304 | MexAM1_META1p0737 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.672 |
ACS40088.1 | topA | MexAM1_META1p2304 | MexAM1_META1p3523 | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.493 |
ACS42111.1 | ACS40088.1 | MexAM1_META1p4480 | MexAM1_META1p2304 | Putative flagellar assembly protein FliH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; structure. | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.446 |
osmC | ACS40088.1 | MexAM1_META1p2305 | MexAM1_META1p2304 | Osmotically inducible protein OsmC; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.545 |
polA | ACS39340.1 | MexAM1_META1p2436 | MexAM1_META1p1478 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Putative DNA polymerase III, delta subunit, holA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.539 |
polA | ACS40088.1 | MexAM1_META1p2436 | MexAM1_META1p2304 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family. | 0.512 |
polA | radA | MexAM1_META1p2436 | MexAM1_META1p4318 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.518 |
polA | recA | MexAM1_META1p2436 | MexAM1_META1p2721 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.983 |
polA | recN | MexAM1_META1p2436 | MexAM1_META1p3158 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.504 |