STRINGSTRING
ACS40147.1 ACS40147.1 purN purN fch fch ACS41473.1 ACS41473.1 mtdA mtdA ACS40048.1 ACS40048.1 ACS40146.1 ACS40146.1 ACS40148.1 ACS40148.1 pheT pheT ACS40149.1 ACS40149.1 ACS42533.1 ACS42533.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ACS40147.1Putative ligase (ygfA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (196 aa)    
Predicted Functional Partners:
purN
Phosphoribosylglycinamide formyltransferase 1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.936
fch
Methenyl tetrahydrofolate cyclohydrolase; Required for both C1 and C2 metabolism; Belongs to the cyclodeaminase/cyclohydrolase family.
    
 0.926
ACS41473.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
  
 
0.915
mtdA
NADP-dependent methylene-tetrahydromethanopterin/methylene- tetrahydrofolate dehydrogenase; Catalyzes the dehydrogenation of methylene-H(4)MPT. Can also catalyze the reversible dehydrogenation of methylene-H(4)F with 20-fold lower catalytic efficiency.
     
  0.900
ACS40048.1
Putative rhomboid-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.715
ACS40146.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.626
ACS40148.1
Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
     
 0.569
pheT
Phenylalanine tRNA synthetase, beta-subunit; Function of strongly homologous gene; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.526
ACS40149.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.454
ACS42533.1
Aminopeptidase; Function of strongly homologous gene; enzyme.
 
   
 0.445
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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