STRINGSTRING
ACS40185.1 ACS40185.1 ACS40184.1 ACS40184.1 secA-2 secA-2 ACS40182.1 ACS40182.1 ACS40194.1 ACS40194.1 ACS40193.1 ACS40193.1 ACS42579.1 ACS42579.1 yajC yajC ftsY ftsY ACS40186.1 ACS40186.1 ACS40181.1 ACS40181.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ACS40185.1TonB-dependent siderophore receptor; Function of strongly homologous gene; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (628 aa)    
Predicted Functional Partners:
ACS40184.1
Peptidase, M50 family protein; Function of strongly homologous gene; enzyme.
 
     0.950
secA-2
Putative preprotein translocase subunit, ATPase (secA-like); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
 
   
 0.944
ACS40182.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
    0.943
ACS40194.1
Hypothetical protein; No homology to any previously reported sequences.
 
     0.742
ACS40193.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.690
ACS42579.1
Signal transduction histidine kinase; Function of strongly homologous gene; regulator.
      
 0.660
yajC
Preprotein translocase, auxillary membrane component (General Secretory Pathway), YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
      
 0.616
ftsY
Fused Signal Recognition Particle (SRP) receptor: membrane binding protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
      
 0.612
ACS40186.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.598
ACS40181.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.553
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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