STRINGSTRING
rpoN rpoN glnG glnG ACS40719.1 ACS40719.1 rpoA rpoA ACS38825.1 ACS38825.1 rpoZ rpoZ rpoB rpoB rpoC rpoC ACS42450.1 ACS42450.1 hfq hfq flbD flbD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
rpoNSigma N (sigma 54) factor of RNA polymerase; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (515 aa)    
Predicted Functional Partners:
glnG
Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 
   
 0.879
ACS40719.1
Putative sigma-54 specific transcriptional regulator, Fis subfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
 0.853
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.846
ACS38825.1
Putative two-component sigma-54 specific transcriptional regulator, Fis subfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   
 0.834
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.815
rpoB
RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.814
rpoC
RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.813
ACS42450.1
Putative trehalose-6-phosphate phosphatase (otsB); Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.807
hfq
Protein hfq, RNA-binding host factor; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
 
  
 0.805
flbD
Two-component flagellar sigma-54 dependent transcriptional regulator, Fis family; Function of strongly homologous gene; regulator.
 
   
 0.796
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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