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hpf hpf ptsN ptsN rpsU rpsU rpmC rpmC rpsI rpsI rpmA rpmA rpmH rpmH rpsP rpsP rplO rplO rpsE rpsE rpsL rpsL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hpfRibosomal subunit interface protein, sigma 54 (RpoN) modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (202 aa)    
Predicted Functional Partners:
ptsN
Sugar-specific enzyme IIA component of PTS; Function of strongly homologous gene; transporter.
  
  
 0.907
rpsU
Ribosomal protein S21; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bS21 family.
   
 
 0.838
rpmC
50S ribosomal subunit protein L29; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the universal ribosomal protein uL29 family.
  
 
 
 0.836
rpsI
Ribosomal protein S9; Function of strongly homologous gene; structure; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.823
rpmA
50S ribosomal protein L27; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.820
rpmH
50S ribosomal subunit protein L34; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the bacterial ribosomal protein bL34 family.
   
 
 0.818
rpsP
Ribosomal protein S16; Function of strongly homologous gene; structure; Belongs to the bacterial ribosomal protein bS16 family.
    
 
 0.813
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.813
rpsE
30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
    
 
 0.813
rpsL
30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
    
 
 0.807
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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