node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS41402.1 | mtnP | MexAM1_META1p3691 | MexAM1_META1p2512 | Putative nucleoside phosphorylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.909 |
ACS42650.1 | mtnP | MexAM1_META1p5046 | MexAM1_META1p2512 | Putative lipase/esterase (aes-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.822 |
apt | guaA | MexAM1_META1p0425 | MexAM1_META1p3135 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.991 |
apt | mtnA | MexAM1_META1p0425 | MexAM1_META1p0488 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative translation initiation factor, aIF-2B alpha subunit (eIF-2B); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.824 |
apt | mtnP | MexAM1_META1p0425 | MexAM1_META1p2512 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.956 |
deoB | guaA | MexAM1_META1p1808 | MexAM1_META1p3135 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.442 |
deoB | mtnP | MexAM1_META1p1808 | MexAM1_META1p2512 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.805 |
guaA | apt | MexAM1_META1p3135 | MexAM1_META1p0425 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.991 |
guaA | deoB | MexAM1_META1p3135 | MexAM1_META1p1808 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.442 |
guaA | mtnP | MexAM1_META1p3135 | MexAM1_META1p2512 | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.529 |
metY | mtnA | MexAM1_META1p2508 | MexAM1_META1p0488 | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative translation initiation factor, aIF-2B alpha subunit (eIF-2B); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.705 |
metY | mtnP | MexAM1_META1p2508 | MexAM1_META1p2512 | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.693 |
metY-2 | mtnA | MexAM1_META1p3362 | MexAM1_META1p0488 | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of strongly homologous gene; enzyme. | Putative translation initiation factor, aIF-2B alpha subunit (eIF-2B); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.705 |
metY-2 | mtnP | MexAM1_META1p3362 | MexAM1_META1p2512 | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of strongly homologous gene; enzyme. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.693 |
metY-3 | mtnA | MexAM1_META1p3547 | MexAM1_META1p0488 | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative translation initiation factor, aIF-2B alpha subunit (eIF-2B); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.705 |
metY-3 | mtnP | MexAM1_META1p3547 | MexAM1_META1p2512 | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.693 |
metY-4 | mtnA | MexAM1_META1p5055 | MexAM1_META1p0488 | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative translation initiation factor, aIF-2B alpha subunit (eIF-2B); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.705 |
metY-4 | mtnP | MexAM1_META1p5055 | MexAM1_META1p2512 | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative 5'-methylthioadenosine phosphorylase (mtnP-like); Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. | 0.693 |
mtnA | apt | MexAM1_META1p0488 | MexAM1_META1p0425 | Putative translation initiation factor, aIF-2B alpha subunit (eIF-2B); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.824 |
mtnA | metY | MexAM1_META1p0488 | MexAM1_META1p2508 | Putative translation initiation factor, aIF-2B alpha subunit (eIF-2B); Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.705 |