STRINGSTRING
ACS40308.1 ACS40308.1 pdhB pdhB ACS38670.1 ACS38670.1 ACS41454.1 ACS41454.1 ACS42480.1 ACS42480.1 ACS42237.1 ACS42237.1 ACS39475.1 ACS39475.1 ACS42072.1 ACS42072.1 ACS39642.1 ACS39642.1 ACS38916.1 ACS38916.1 cckA cckA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACS40308.1Putative histidine kinase with HK Homodimeric domain, ATPase domain and a sensory PAS domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (843 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.871
ACS38670.1
Putative response regulator receiver; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 
 0.839
ACS41454.1
Putative sensor protein gacS (Synonyms : lemA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
0.834
ACS42480.1
Putative PAS sensor hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 
 
0.826
ACS42237.1
Putative response regulator receiver; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.819
ACS39475.1
Hypothetical protein; No homology to any previously reported sequences.
 
 
0.772
ACS42072.1
Putative hybrid histidine kinase with multiple PAS and a response regulator receiver domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 
 0.766
ACS39642.1
Putative sensor and regulator, histidine kinase and CheY-like receiver domains; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
   0.728
ACS38916.1
Integral membrane sensor signal transduction histidine kinase; Function of strongly homologous gene; regulator.
  
 
   0.722
cckA
Sensor hybrid histidine kinase with multiple PAS and response regulator receiver domains; Function of strongly homologous gene; regulator.
 
 
 
 0.718
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.