STRINGSTRING
ycbL ycbL ACS42311.1 ACS42311.1 gloB gloB ACS38307.1 ACS38307.1 ldhA ldhA ACS40700.1 ACS40700.1 ACS39663.1 ACS39663.1 gyrB gyrB yciA yciA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ycbLPutative metal-binding hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (214 aa)    
Predicted Functional Partners:
ACS42311.1
Putative lactoylglutathione lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.919
gloB
Putative hydroxyacylglutathione hydrolase (gloB-like) with metallo-hydrolase/oxidoreductase domain; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
  
0.912
ACS38307.1
Putative lactoylglutathione lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.908
ldhA
Fermentative D-lactate dehydrogenase, NAD-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 0.904
ACS40700.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.706
ACS39663.1
Putative fatty acid synthase multidomain protein (rkpA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.496
gyrB
DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...]
     
 0.496
yciA
acyl-CoA thioester hydrolase; Function of strongly homologous gene; putative enzyme.
  
    0.468
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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