node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40350.1 | ACS40351.1 | MexAM1_META1p2574 | MexAM1_META1p2575 | Thioredoxin-related; Function of strongly homologous gene; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.664 |
ACS40350.1 | ACS40352.1 | MexAM1_META1p2574 | MexAM1_META1p2576 | Thioredoxin-related; Function of strongly homologous gene; enzyme. | Hypothetical protein; No homology to any previously reported sequences. | 0.480 |
ACS40351.1 | ACS40350.1 | MexAM1_META1p2575 | MexAM1_META1p2574 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Thioredoxin-related; Function of strongly homologous gene; enzyme. | 0.664 |
ACS40351.1 | ACS40352.1 | MexAM1_META1p2575 | MexAM1_META1p2576 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Hypothetical protein; No homology to any previously reported sequences. | 0.551 |
ACS40351.1 | ACS40794.1 | MexAM1_META1p2575 | MexAM1_META1p3046 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Cytochrome c, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.406 |
ACS40351.1 | gyrB | MexAM1_META1p2575 | MexAM1_META1p2546 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | 0.516 |
ACS40351.1 | parE | MexAM1_META1p2575 | MexAM1_META1p3331 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.516 |
ACS40352.1 | ACS40350.1 | MexAM1_META1p2576 | MexAM1_META1p2574 | Hypothetical protein; No homology to any previously reported sequences. | Thioredoxin-related; Function of strongly homologous gene; enzyme. | 0.480 |
ACS40352.1 | ACS40351.1 | MexAM1_META1p2576 | MexAM1_META1p2575 | Hypothetical protein; No homology to any previously reported sequences. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.551 |
ACS40794.1 | ACS40351.1 | MexAM1_META1p3046 | MexAM1_META1p2575 | Cytochrome c, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.406 |
ACS40794.1 | gyrB | MexAM1_META1p3046 | MexAM1_META1p2546 | Cytochrome c, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | 0.550 |
ACS40794.1 | parE | MexAM1_META1p3046 | MexAM1_META1p3331 | Cytochrome c, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.550 |
gyrB | ACS40351.1 | MexAM1_META1p2546 | MexAM1_META1p2575 | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.516 |
gyrB | ACS40794.1 | MexAM1_META1p2546 | MexAM1_META1p3046 | DNA gyrase, subunit B (type II topoisomerase); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...] | Cytochrome c, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.550 |
parE | ACS40351.1 | MexAM1_META1p3331 | MexAM1_META1p2575 | DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.516 |
parE | ACS40794.1 | MexAM1_META1p3331 | MexAM1_META1p3046 | DNA topoisomerase IV, subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | Cytochrome c, class I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.550 |