STRINGSTRING
lspA-2 lspA-2 lspA lspA zntA zntA ileS ileS murJ murJ omp omp ACS38757.1 ACS38757.1 ACS40374.1 ACS40374.1 hmrR hmrR lon lon ACS40373.1 ACS40373.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lspA-2Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (160 aa)    
Predicted Functional Partners:
lspA
Lipoprotein signal peptidase (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
  
  
 
0.921
zntA
Zinc, cadmium, cobalt and lead efflux system; Function of strongly homologous gene; transporter.
  
    0.697
ileS
Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
 
  
 0.673
murJ
Putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
 
   
 0.634
omp
Outer membrane lipoprotein omp16 precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
   
 0.559
ACS38757.1
Putative Lipoprotein releasing system, transmembrane protein, LolC/E family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
   
 0.552
ACS40374.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.550
hmrR
Heavy metal resistance transcriptional regulator HmrR, MerR family; Function of strongly homologous gene; putative regulator.
     
 0.497
lon
ATP-dependent protease La (Lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
   
 0.480
ACS40373.1
Cytochrome biogenesis protein (CcdA, CdcA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.477
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (22%) [HD]