node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38757.1 | lspA-2 | MexAM1_META1p0836 | MexAM1_META1p2600 | Putative Lipoprotein releasing system, transmembrane protein, LolC/E family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.552 |
ACS38757.1 | omp | MexAM1_META1p0836 | MexAM1_META1p5302 | Putative Lipoprotein releasing system, transmembrane protein, LolC/E family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | Outer membrane lipoprotein omp16 precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.750 |
ACS40373.1 | ACS40374.1 | MexAM1_META1p2598 | MexAM1_META1p2599 | Cytochrome biogenesis protein (CcdA, CdcA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.658 |
ACS40373.1 | lspA-2 | MexAM1_META1p2598 | MexAM1_META1p2600 | Cytochrome biogenesis protein (CcdA, CdcA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.477 |
ACS40373.1 | zntA | MexAM1_META1p2598 | MexAM1_META1p2601 | Cytochrome biogenesis protein (CcdA, CdcA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Zinc, cadmium, cobalt and lead efflux system; Function of strongly homologous gene; transporter. | 0.430 |
ACS40374.1 | ACS40373.1 | MexAM1_META1p2599 | MexAM1_META1p2598 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Cytochrome biogenesis protein (CcdA, CdcA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.658 |
ACS40374.1 | lspA-2 | MexAM1_META1p2599 | MexAM1_META1p2600 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.550 |
ACS40374.1 | zntA | MexAM1_META1p2599 | MexAM1_META1p2601 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Zinc, cadmium, cobalt and lead efflux system; Function of strongly homologous gene; transporter. | 0.485 |
hmrR | lspA-2 | MexAM1_META1p2602 | MexAM1_META1p2600 | Heavy metal resistance transcriptional regulator HmrR, MerR family; Function of strongly homologous gene; putative regulator. | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.497 |
hmrR | zntA | MexAM1_META1p2602 | MexAM1_META1p2601 | Heavy metal resistance transcriptional regulator HmrR, MerR family; Function of strongly homologous gene; putative regulator. | Zinc, cadmium, cobalt and lead efflux system; Function of strongly homologous gene; transporter. | 0.630 |
ileS | lspA | MexAM1_META1p2327 | MexAM1_META1p2328 | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | Lipoprotein signal peptidase (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.964 |
ileS | lspA-2 | MexAM1_META1p2327 | MexAM1_META1p2600 | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.673 |
lon | lspA-2 | MexAM1_META1p2421 | MexAM1_META1p2600 | ATP-dependent protease La (Lon); ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.480 |
lspA | ileS | MexAM1_META1p2328 | MexAM1_META1p2327 | Lipoprotein signal peptidase (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Isoleucine tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). | 0.964 |
lspA | lspA-2 | MexAM1_META1p2328 | MexAM1_META1p2600 | Lipoprotein signal peptidase (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.921 |
lspA | murJ | MexAM1_META1p2328 | MexAM1_META1p3511 | Lipoprotein signal peptidase (Prolipoprotein signal peptidase) (Signal peptidase II) (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Putative peptidoglycan lipid II flippase protein, MurJ (MviN)-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.440 |
lspA-2 | ACS38757.1 | MexAM1_META1p2600 | MexAM1_META1p0836 | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Putative Lipoprotein releasing system, transmembrane protein, LolC/E family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.552 |
lspA-2 | ACS40373.1 | MexAM1_META1p2600 | MexAM1_META1p2598 | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Cytochrome biogenesis protein (CcdA, CdcA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.477 |
lspA-2 | ACS40374.1 | MexAM1_META1p2600 | MexAM1_META1p2599 | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.550 |
lspA-2 | hmrR | MexAM1_META1p2600 | MexAM1_META1p2602 | Putative prolipoprotein signal peptidase (SPase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | Heavy metal resistance transcriptional regulator HmrR, MerR family; Function of strongly homologous gene; putative regulator. | 0.497 |