STRINGSTRING
hmrR hmrR ACS42480.1 ACS42480.1 ACS38807.1 ACS38807.1 rpoB rpoB zntA zntA merT merT ACS39682.1 ACS39682.1 dnaJ dnaJ ACS41179.1 ACS41179.1 ACS42318.1 ACS42318.1 ACS42858.1 ACS42858.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hmrRHeavy metal resistance transcriptional regulator HmrR, MerR family; Function of strongly homologous gene; putative regulator. (133 aa)    
Predicted Functional Partners:
ACS42480.1
Putative PAS sensor hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
   
 
 0.729
ACS38807.1
Multidrug resistance efflux pump; Function of strongly homologous gene; transporter.
      
 0.690
rpoB
RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.640
zntA
Zinc, cadmium, cobalt and lead efflux system; Function of strongly homologous gene; transporter.
  
  
 0.630
merT
Mercuric transport protein (Mercury ion transport protein); Function of strongly homologous gene; transporter.
 
  
 0.581
ACS39682.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.542
dnaJ
Heat shock protein (Hsp40), co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent [...]
  
 
 0.542
ACS41179.1
Putative chaperone protein, DnaJ domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
 
 0.542
ACS42318.1
Chaperone DnaJ domain protein, putative heat shock protein; Function of strongly homologous gene; factor.
  
 
 0.542
ACS42858.1
Conserved hypothetical protein, containing N-terminal fragment of heat shock protein DnaJ; Homologs of previously reported genes of unknown function.
  
 
 0.542
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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