STRINGSTRING
thrB thrB hom hom thrC thrC metH metH ilvE ilvE ACS42657.1 ACS42657.1 ahcY ahcY metY metY metY-2 metY-2 metY-3 metY-3 metY-4 metY-4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
thrBHomoserine kinase; Function of strongly homologous gene; enzyme; Belongs to the pseudomonas-type ThrB family. (321 aa)    
Predicted Functional Partners:
hom
Homoserine dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.949
thrC
Threonine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.937
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.820
ilvE
Putative branched-chain amino acid transferase (ilvE-like); Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.812
ACS42657.1
Putative branched-chain amino acid aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.812
ahcY
S-adenosyl L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.806
metY
Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.805
metY-2
Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of strongly homologous gene; enzyme.
    
  0.805
metY-3
Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.805
metY-4
Trans-sulfuration enzyme (O-acetylhomoserine aminocarboxypropyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.805
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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