Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACS40480.1 | ACS40481.1 | MexAM1_META1p2715 | MexAM1_META1p2716 | Putative peroxiredoxin protein, antioxidant protein, AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | 0.604 |
| ACS40481.1 | ACS40480.1 | MexAM1_META1p2716 | MexAM1_META1p2715 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | Putative peroxiredoxin protein, antioxidant protein, AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. | 0.604 |
| ACS40481.1 | ACS41269.1 | MexAM1_META1p2716 | MexAM1_META1p3534 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.853 |
| ACS40481.1 | dnaN | MexAM1_META1p2716 | MexAM1_META1p0002 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.811 |
| ACS40481.1 | dut | MexAM1_META1p2716 | MexAM1_META1p1415 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.785 |
| ACS40481.1 | hflC | MexAM1_META1p2716 | MexAM1_META1p2850 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | 0.556 |
| ACS40481.1 | hflK | MexAM1_META1p2716 | MexAM1_META1p2851 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | 0.556 |
| ACS40481.1 | nrd | MexAM1_META1p2716 | MexAM1_META1p0872 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.988 |
| ACS40481.1 | sdhD | MexAM1_META1p2716 | MexAM1_META1p3860 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | Succinate dehydrogenase delta subunit; Function of strongly homologous gene; enzyme. | 0.749 |
| ACS40481.1 | secB | MexAM1_META1p2716 | MexAM1_META1p1450 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. | 0.642 |
| ACS40481.1 | thyA | MexAM1_META1p2716 | MexAM1_META1p2853 | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.762 |
| ACS41269.1 | ACS40481.1 | MexAM1_META1p3534 | MexAM1_META1p2716 | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | 0.853 |
| dnaN | ACS40481.1 | MexAM1_META1p0002 | MexAM1_META1p2716 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | 0.811 |
| dnaN | dut | MexAM1_META1p0002 | MexAM1_META1p1415 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | 0.864 |
| dnaN | nrd | MexAM1_META1p0002 | MexAM1_META1p0872 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.863 |
| dnaN | thyA | MexAM1_META1p0002 | MexAM1_META1p2853 | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.871 |
| dut | ACS40481.1 | MexAM1_META1p1415 | MexAM1_META1p2716 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Conserved hypothetical protein, UPF0301 protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0301 (AlgH) family. | 0.785 |
| dut | dnaN | MexAM1_META1p1415 | MexAM1_META1p0002 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.864 |
| dut | nrd | MexAM1_META1p1415 | MexAM1_META1p0872 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.875 |
| dut | thyA | MexAM1_META1p1415 | MexAM1_META1p2853 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.979 |
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