node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40521.1 | gcvH | MexAM1_META1p2761 | MexAM1_META1p0621 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.972 |
ACS40521.1 | gcvP | MexAM1_META1p2761 | MexAM1_META1p0620 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.931 |
ACS40521.1 | mtkA | MexAM1_META1p2761 | MexAM1_META1p1730 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | 0.713 |
ACS40521.1 | pdhB | MexAM1_META1p2761 | MexAM1_META1p2987 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.820 |
ACS40521.1 | soxB | MexAM1_META1p2761 | MexAM1_META1p1548 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Sarcosine oxidase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.824 |
ACS40521.1 | soxB-3 | MexAM1_META1p2761 | MexAM1_META1p4108 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Sarcosine oxidase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.819 |
ACS40521.1 | soxD | MexAM1_META1p2761 | MexAM1_META1p1547 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Sarcosine oxidase, delta subunit; Function of strongly homologous gene; enzyme. | 0.778 |
ACS40521.1 | soxD-2 | MexAM1_META1p2761 | MexAM1_META1p4109 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Sarcosine oxidase, delta subunit; Function of strongly homologous gene; enzyme. | 0.778 |
ACS40521.1 | soxG | MexAM1_META1p2761 | MexAM1_META1p1545 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | Sarcosine oxidase, gamma subunit; Function of strongly homologous gene; enzyme. | 0.719 |
ACS40521.1 | sucC | MexAM1_META1p2761 | MexAM1_META1p1538 | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.713 |
gcvH | ACS40521.1 | MexAM1_META1p0621 | MexAM1_META1p2761 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | 0.972 |
gcvH | gcvP | MexAM1_META1p0621 | MexAM1_META1p0620 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH | pdhB | MexAM1_META1p0621 | MexAM1_META1p2987 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.884 |
gcvP | ACS40521.1 | MexAM1_META1p0620 | MexAM1_META1p2761 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the GcvT family. | 0.931 |
gcvP | gcvH | MexAM1_META1p0620 | MexAM1_META1p0621 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
gcvP | mtkA | MexAM1_META1p0620 | MexAM1_META1p1730 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Malate thiokinase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate/malate CoA ligase beta subunit family. | 0.853 |
gcvP | pdhB | MexAM1_META1p0620 | MexAM1_META1p2987 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.794 |
gcvP | soxB-3 | MexAM1_META1p0620 | MexAM1_META1p4108 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.929 |
gcvP | soxD | MexAM1_META1p0620 | MexAM1_META1p1547 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase, delta subunit; Function of strongly homologous gene; enzyme. | 0.448 |
gcvP | soxD-2 | MexAM1_META1p0620 | MexAM1_META1p4109 | Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase, delta subunit; Function of strongly homologous gene; enzyme. | 0.942 |