ACS40524.1 protein (Methylorubrum extorquens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ACS40524.1

Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (187 aa)

Predicted Functional Partners:

emrE

0.796

ACS42367.1

0.641

acrA

0.623

ACS40522.1

0.516

ACS42218.1

0.437

Your Current Organism:

Methylorubrum extorquens

NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACS40522.1	ACS40524.1	MexAM1_META1p2762	MexAM1_META1p2764	Multidrug efflux system protein (acrB ou acrF); Function of homologous gene experimentally demonstrated in an other organism; transporter.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.516
ACS40522.1	acrA	MexAM1_META1p2762	MexAM1_META1p2763	Multidrug efflux system protein (acrB ou acrF); Function of homologous gene experimentally demonstrated in an other organism; transporter.	Multidrug efflux system; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.993
ACS40522.1	emrE	MexAM1_META1p2762	MexAM1_META1p2765	Multidrug efflux system protein (acrB ou acrF); Function of homologous gene experimentally demonstrated in an other organism; transporter.	Small multidrug efflux pump, DMT superfamily; Function of strongly homologous gene; transporter.	0.532
ACS40524.1	ACS40522.1	MexAM1_META1p2764	MexAM1_META1p2762	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Multidrug efflux system protein (acrB ou acrF); Function of homologous gene experimentally demonstrated in an other organism; transporter.	0.516
ACS40524.1	ACS42218.1	MexAM1_META1p2764	MexAM1_META1p4589	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.437
ACS40524.1	ACS42367.1	MexAM1_META1p2764	MexAM1_META1p4739	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Putative transcriptional regulator, TetR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.	0.641
ACS40524.1	acrA	MexAM1_META1p2764	MexAM1_META1p2763	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Multidrug efflux system; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.623
ACS40524.1	emrE	MexAM1_META1p2764	MexAM1_META1p2765	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Small multidrug efflux pump, DMT superfamily; Function of strongly homologous gene; transporter.	0.796
ACS42218.1	ACS40524.1	MexAM1_META1p4589	MexAM1_META1p2764	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.437
ACS42367.1	ACS40524.1	MexAM1_META1p4739	MexAM1_META1p2764	Putative transcriptional regulator, TetR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.641
acrA	ACS40522.1	MexAM1_META1p2763	MexAM1_META1p2762	Multidrug efflux system; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Multidrug efflux system protein (acrB ou acrF); Function of homologous gene experimentally demonstrated in an other organism; transporter.	0.993
acrA	ACS40524.1	MexAM1_META1p2763	MexAM1_META1p2764	Multidrug efflux system; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.623
acrA	emrE	MexAM1_META1p2763	MexAM1_META1p2765	Multidrug efflux system; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Small multidrug efflux pump, DMT superfamily; Function of strongly homologous gene; transporter.	0.634
emrE	ACS40522.1	MexAM1_META1p2765	MexAM1_META1p2762	Small multidrug efflux pump, DMT superfamily; Function of strongly homologous gene; transporter.	Multidrug efflux system protein (acrB ou acrF); Function of homologous gene experimentally demonstrated in an other organism; transporter.	0.532
emrE	ACS40524.1	MexAM1_META1p2765	MexAM1_META1p2764	Small multidrug efflux pump, DMT superfamily; Function of strongly homologous gene; transporter.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.796
emrE	acrA	MexAM1_META1p2765	MexAM1_META1p2763	Small multidrug efflux pump, DMT superfamily; Function of strongly homologous gene; transporter.	Multidrug efflux system; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.634