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ccmA ccmA ccmB ccmB ccmC ccmC cycJ cycJ cycL cycL cycK cycK ccmG ccmG lolD lolD cycH cycH ACS39583.1 ACS39583.1 rpsI rpsI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ccmAHeme export protein, cytochrome C-type biogenesis ccmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (215 aa)    
Predicted Functional Partners:
ccmB
Heme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 0.999
ccmC
Heme exporter protein, cytochrome c-type biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.992
cycJ
Cytochrome c-type biogenesis protein CycJ; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.881
cycL
Cytochrome c-type biogenesis protein CycL precursor; Possible subunit of a heme lyase.
 
   
 0.840
cycK
Cytochrome c-type biogenesis protein CycK; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.818
ccmG
Periplasmic protein thiol:disulfide oxidoreductase, cytochrome c-type biogenesis; Function of strongly homologous gene; enzyme.
 
   
 0.780
lolD
Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
    0.731
cycH
Cytochrome c-type biogenesis protein CycH; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
   
 0.711
ACS39583.1
ABC transporter ATP-binding protein (subunit C); Function of homologous gene experimentally demonstrated in an other organism; transporter.
  
     0.620
rpsI
Ribosomal protein S9; Function of strongly homologous gene; structure; Belongs to the universal ribosomal protein uS9 family.
  
   
 0.555
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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