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nadA nadA ACS40589.1 ACS40589.1 nadC nadC ACS42524.1 ACS42524.1 ACS41987.1 ACS41987.1 gmk gmk cysE cysE cysE-2 cysE-2 valS valS iscS iscS bioB bioB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nadAPutative quinolinate synthetase A (nadA-like); Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (347 aa)    
Predicted Functional Partners:
ACS40589.1
Putative L-aspartate oxidase (nadB-like); Catalyzes the oxidation of L-aspartate to iminoaspartate.
 0.999
nadC
Nicotinate-mononucleotide pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family.
 
 0.999
ACS42524.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
    0.926
ACS41987.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
    0.834
gmk
Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP.
  
    0.806
cysE
Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.796
cysE-2
Serine acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.796
valS
Valine tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
      0.680
iscS
Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Function of strongly homologous gene; enzyme.
  
  
 0.559
bioB
Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
  
 0.549
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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