STRINGSTRING
nadC nadC nadA nadA ACS40589.1 ACS40589.1 pncB pncB nadD nadD ACS40765.1 ACS40765.1 mazG mazG surE surE ACS42500.1 ACS42500.1 ACS39227.1 ACS39227.1 ACS42524.1 ACS42524.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
nadCNicotinate-mononucleotide pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family. (286 aa)    
Predicted Functional Partners:
nadA
Putative quinolinate synthetase A (nadA-like); Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
 0.999
ACS40589.1
Putative L-aspartate oxidase (nadB-like); Catalyzes the oxidation of L-aspartate to iminoaspartate.
  
 0.999
pncB
Nicotinate phosphoribosyltransferase (NAPRTase); Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
   
 0.944
nadD
Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.932
ACS40765.1
CinA (competence-damaged protein) family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the CinA family.
     
 0.921
mazG
Nucleoside triphosphate pyrophosphohydrolase MazG; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
  0.907
surE
5'-nucleotidase surE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.906
ACS42500.1
Putative nucleotide pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.902
ACS39227.1
Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family.
     
  0.900
ACS42524.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
    0.895
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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