node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40602.1 | hflC | MexAM1_META1p2849 | MexAM1_META1p2850 | Putative serine protease precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S1C family. | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | 0.672 |
ACS40602.1 | hflK | MexAM1_META1p2849 | MexAM1_META1p2851 | Putative serine protease precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S1C family. | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | 0.680 |
ACS40602.1 | secY | MexAM1_META1p2849 | MexAM1_META1p2172 | Putative serine protease precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S1C family. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.405 |
ftsH | hflC | MexAM1_META1p5299 | MexAM1_META1p2850 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | 0.915 |
ftsH | hflK | MexAM1_META1p5299 | MexAM1_META1p2851 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | 0.979 |
ftsH | hflX | MexAM1_META1p5299 | MexAM1_META1p3026 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative GTPase (HflX); GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.612 |
ftsH | oxaA | MexAM1_META1p5299 | MexAM1_META1p2354 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Transmembrane protein, OxaA-like, preprotein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.437 |
ftsH | secY | MexAM1_META1p5299 | MexAM1_META1p2172 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.737 |
ftsH | sppA | MexAM1_META1p5299 | MexAM1_META1p0053 | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.748 |
hflC | ACS40602.1 | MexAM1_META1p2850 | MexAM1_META1p2849 | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | Putative serine protease precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S1C family. | 0.672 |
hflC | ftsH | MexAM1_META1p2850 | MexAM1_META1p5299 | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.915 |
hflC | hflK | MexAM1_META1p2850 | MexAM1_META1p2851 | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | 0.999 |
hflC | hflX | MexAM1_META1p2850 | MexAM1_META1p3026 | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | Putative GTPase (HflX); GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.554 |
hflC | oxaA | MexAM1_META1p2850 | MexAM1_META1p2354 | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | Transmembrane protein, OxaA-like, preprotein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.539 |
hflK | ACS40602.1 | MexAM1_META1p2851 | MexAM1_META1p2849 | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | Putative serine protease precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S1C family. | 0.680 |
hflK | ftsH | MexAM1_META1p2851 | MexAM1_META1p5299 | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | Cell division protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.979 |
hflK | hflC | MexAM1_META1p2851 | MexAM1_META1p2850 | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | HflC protein precursor, modulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could regulate a protease. | 0.999 |
hflK | hflX | MexAM1_META1p2851 | MexAM1_META1p3026 | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | Putative GTPase (HflX); GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.860 |
hflK | oxaA | MexAM1_META1p2851 | MexAM1_META1p2354 | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | Transmembrane protein, OxaA-like, preprotein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.774 |
hflK | plsX | MexAM1_META1p2851 | MexAM1_META1p2035 | Protease subunit hflK; HflC and HflK could encode or regulate a protease. | Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. | 0.660 |