node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38075.1 | ACS39304.1 | MexAM1_META1p0108 | MexAM1_META1p1442 | Putative 4Fe-4S ferredoxin, iron-sulfur binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.494 |
ACS38075.1 | ACS40653.1 | MexAM1_META1p0108 | MexAM1_META1p2900 | Putative 4Fe-4S ferredoxin, iron-sulfur binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Hypothetical protein; No homology to any previously reported sequences. | 0.405 |
ACS38075.1 | moaA | MexAM1_META1p0108 | MexAM1_META1p2843 | Putative 4Fe-4S ferredoxin, iron-sulfur binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Molybdenum biosynthetic protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.465 |
ACS39304.1 | ACS38075.1 | MexAM1_META1p1442 | MexAM1_META1p0108 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative 4Fe-4S ferredoxin, iron-sulfur binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.494 |
ACS39304.1 | ACS40653.1 | MexAM1_META1p1442 | MexAM1_META1p2900 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Hypothetical protein; No homology to any previously reported sequences. | 0.650 |
ACS39304.1 | cysG | MexAM1_META1p1442 | MexAM1_META1p3434 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.908 |
ACS40653.1 | ACS38075.1 | MexAM1_META1p2900 | MexAM1_META1p0108 | Hypothetical protein; No homology to any previously reported sequences. | Putative 4Fe-4S ferredoxin, iron-sulfur binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.405 |
ACS40653.1 | ACS39304.1 | MexAM1_META1p2900 | MexAM1_META1p1442 | Hypothetical protein; No homology to any previously reported sequences. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.650 |
ACS40653.1 | ACS40654.1 | MexAM1_META1p2900 | MexAM1_META1p2901 | Hypothetical protein; No homology to any previously reported sequences. | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.523 |
ACS40653.1 | cysG | MexAM1_META1p2900 | MexAM1_META1p3434 | Hypothetical protein; No homology to any previously reported sequences. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.824 |
ACS40653.1 | fsr | MexAM1_META1p2900 | MexAM1_META1p0808 | Hypothetical protein; No homology to any previously reported sequences. | Multidrug transport protein (MFS family); Function of strongly homologous gene; transporter. | 0.586 |
ACS40653.1 | moaA | MexAM1_META1p2900 | MexAM1_META1p2843 | Hypothetical protein; No homology to any previously reported sequences. | Molybdenum biosynthetic protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.510 |
ACS40653.1 | narK | MexAM1_META1p2900 | MexAM1_META1p0196 | Hypothetical protein; No homology to any previously reported sequences. | Putative nitrate transporter narK; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.586 |
ACS40653.1 | oxlT-4 | MexAM1_META1p2900 | MexAM1_META1p1925 | Hypothetical protein; No homology to any previously reported sequences. | Putative oxalate/formate antiporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.586 |
ACS40653.1 | oxlT-5 | MexAM1_META1p2900 | MexAM1_META1p2127 | Hypothetical protein; No homology to any previously reported sequences. | Putative oxalate/formate antiporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.586 |
ACS40653.1 | speG | MexAM1_META1p2900 | MexAM1_META1p2899 | Hypothetical protein; No homology to any previously reported sequences. | Spermidine N1-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.551 |
ACS40654.1 | ACS40653.1 | MexAM1_META1p2901 | MexAM1_META1p2900 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | Hypothetical protein; No homology to any previously reported sequences. | 0.523 |
cysG | ACS39304.1 | MexAM1_META1p3434 | MexAM1_META1p1442 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.908 |
cysG | ACS40653.1 | MexAM1_META1p3434 | MexAM1_META1p2900 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Hypothetical protein; No homology to any previously reported sequences. | 0.824 |
cysG | fsr | MexAM1_META1p3434 | MexAM1_META1p0808 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Multidrug transport protein (MFS family); Function of strongly homologous gene; transporter. | 0.543 |