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crtE crtE crtB crtB crtF crtF bchP bchP uppS-2 uppS-2 uppS uppS ispH ispH ispA ispA ACS40674.1 ACS40674.1 ispB ispB bchC bchC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
crtEGeranylgeranyl pyrophosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family. (288 aa)    
Predicted Functional Partners:
crtB
Phytoene synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.984
crtF
Hydroxyneurosporene methyltransferase CrtF; Function of strongly homologous gene; enzyme.
  
 0.983
bchP
Geranylgeranyl reductase; Function of strongly homologous gene; enzyme.
 
 0.982
uppS-2
Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.960
uppS
Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.954
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
 
 0.927
ispA
Geranyltranstransferase (farnesyl-diphosphate synthase); Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
  
  
 
0.920
ACS40674.1
Putative hydroxyneurosporene dehydrogenase (Hydroxyneurosporene synthase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.919
ispB
Octaprenyl diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
  
  
0.917
bchC
2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase; Function of strongly homologous gene; enzyme.
 
 
 0.892
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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