node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38194.1 | kdsA | MexAM1_META1p0232 | MexAM1_META1p2981 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | 0.906 |
ACS38194.1 | kdsB | MexAM1_META1p0232 | MexAM1_META1p0233 | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.974 |
ACS40728.1 | kdsA | MexAM1_META1p2980 | MexAM1_META1p2981 | Hypothetical protein; No homology to any previously reported sequences. | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | 0.785 |
kdsA | ACS38194.1 | MexAM1_META1p2981 | MexAM1_META1p0232 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.906 |
kdsA | ACS40728.1 | MexAM1_META1p2981 | MexAM1_META1p2980 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | Hypothetical protein; No homology to any previously reported sequences. | 0.785 |
kdsA | kdsB | MexAM1_META1p2981 | MexAM1_META1p0233 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.851 |
kdsA | kdsD | MexAM1_META1p2981 | MexAM1_META1p3866 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | Arabinose-5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.988 |
kdsA | lpxA | MexAM1_META1p2981 | MexAM1_META1p5125 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.939 |
kdsA | lpxB | MexAM1_META1p2981 | MexAM1_META1p5127 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.841 |
kdsA | lpxC | MexAM1_META1p2981 | MexAM1_META1p3155 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.941 |
kdsA | lpxD | MexAM1_META1p2981 | MexAM1_META1p2065 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.823 |
kdsA | lpxK | MexAM1_META1p2981 | MexAM1_META1p3173 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.946 |
kdsA | waaA | MexAM1_META1p2981 | MexAM1_META1p3174 | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.847 |
kdsB | ACS38194.1 | MexAM1_META1p0233 | MexAM1_META1p0232 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Putative Prephenate dehydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.974 |
kdsB | kdsA | MexAM1_META1p0233 | MexAM1_META1p2981 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 3-deoxy-8-phosphooctulonate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family. | 0.851 |
kdsB | kdsD | MexAM1_META1p0233 | MexAM1_META1p3866 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Arabinose-5-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.881 |
kdsB | lpxA | MexAM1_META1p0233 | MexAM1_META1p5125 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.844 |
kdsB | lpxB | MexAM1_META1p0233 | MexAM1_META1p5127 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.845 |
kdsB | lpxC | MexAM1_META1p0233 | MexAM1_META1p3155 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.841 |
kdsB | lpxD | MexAM1_META1p0233 | MexAM1_META1p2065 | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.843 |