STRINGSTRING
ACS40749.1 ACS40749.1 ubiG ubiG lipA lipA ubiA ubiA rrmJ rrmJ ACS39530.1 ACS39530.1 ubiH ubiH ACS39874.1 ACS39874.1 secB secB ACS38133.1 ACS38133.1 ubiB ubiB
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ACS40749.1Cyclase/dehydrase; Function of strongly homologous gene; enzyme. (136 aa)    
Predicted Functional Partners:
ubiG
Putative UbiG: ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
   
 0.737
lipA
Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
       0.651
ubiA
P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
  
 
 
 0.599
rrmJ
Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
 
    0.517
ACS39530.1
Putative 1-acylglycerol-3-phosphate O-acyltransferase (plsC); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.509
ubiH
2-octaprenyl-6-methoxyphenol hydroxylase (FAD-dependent oxidoreductase); Function of strongly homologous gene; enzyme.
  
   
 0.504
ACS39874.1
Putative ubiquinone biosynthesis hydroxylase/monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
   
 0.469
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
     0.462
ACS38133.1
Conserved hypothetical protein with putative domain ATP12 chaperone protein; Homologs of previously reported genes of unknown function.
  
   
 0.458
ubiB
Ubiquinone biosynthesis protein, putative 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
  
 
 
 0.456
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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