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ntrY ntrY glnG-2 glnG-2 ACS42480.1 ACS42480.1 fliF fliF fliF-2 fliF-2 glnG glnG ACS39475.1 ACS39475.1 mscL mscL asdB asdB phyR phyR flhA flhA
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ntrYNitrogen regulatory signal transduction histidine kinase NtrY; Function of strongly homologous gene; enzyme. (789 aa)    
Predicted Functional Partners:
glnG-2
Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator.
 0.995
ACS42480.1
Putative PAS sensor hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor.
 
 
 
 0.831
fliF
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
  
 0.794
fliF-2
Flagellar biosynthesis; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
  
 0.794
glnG
Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 
 0.793
ACS39475.1
Hypothetical protein; No homology to any previously reported sequences.
   
 
 0.705
mscL
Mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
      
 0.666
asdB
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
      
 0.662
phyR
PhyR; Key regulator for adaptation to epiphytic life (leaf colonizing) of the bacterium. Positively regulates several genes including katE, sodA, hsp20, dps and gloA. However, it is not known whether this regulation is direct or indirect. Also induces several dehydrogenases.
    
 
 0.638
flhA
Flagellar export protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
   
  
 0.622
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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