node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS38189.1 | amtB | MexAM1_META1p0227 | MexAM1_META1p2088 | Transporter protein; Function of strongly homologous gene; transporter. | Ammonium transport protein (Amt family); Function of strongly homologous gene; transporter. | 0.487 |
ACS38189.1 | cysG | MexAM1_META1p0227 | MexAM1_META1p3434 | Transporter protein; Function of strongly homologous gene; transporter. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.400 |
ACS38189.1 | glnG-2 | MexAM1_META1p0227 | MexAM1_META1p3024 | Transporter protein; Function of strongly homologous gene; transporter. | Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator. | 0.662 |
ACS38189.1 | mutM | MexAM1_META1p0227 | MexAM1_META1p4436 | Transporter protein; Function of strongly homologous gene; transporter. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.404 |
ACS38189.1 | pnp | MexAM1_META1p0227 | MexAM1_META1p4416 | Transporter protein; Function of strongly homologous gene; transporter. | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.404 |
ACS39283.1 | glnG-2 | MexAM1_META1p1421 | MexAM1_META1p3024 | Two-component system, chemotaxis family, sensor kinase CheA; Function of strongly homologous gene; enzyme. | Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator. | 0.661 |
ACS39283.1 | ntrY | MexAM1_META1p1421 | MexAM1_META1p3023 | Two-component system, chemotaxis family, sensor kinase CheA; Function of strongly homologous gene; enzyme. | Nitrogen regulatory signal transduction histidine kinase NtrY; Function of strongly homologous gene; enzyme. | 0.447 |
ACS41320.1 | fmdD | MexAM1_META1p3607 | MexAM1_META1p0979 | Putative branched-chain amino acid ABC transporter, substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter. | Short-chain amide-urea binding porin; Function of strongly homologous gene; factor. | 0.901 |
ACS41320.1 | glnG-2 | MexAM1_META1p3607 | MexAM1_META1p3024 | Putative branched-chain amino acid ABC transporter, substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter. | Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator. | 0.683 |
amtB | ACS38189.1 | MexAM1_META1p2088 | MexAM1_META1p0227 | Ammonium transport protein (Amt family); Function of strongly homologous gene; transporter. | Transporter protein; Function of strongly homologous gene; transporter. | 0.487 |
amtB | cysG | MexAM1_META1p2088 | MexAM1_META1p3434 | Ammonium transport protein (Amt family); Function of strongly homologous gene; transporter. | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.799 |
amtB | glnG-2 | MexAM1_META1p2088 | MexAM1_META1p3024 | Ammonium transport protein (Amt family); Function of strongly homologous gene; transporter. | Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator. | 0.661 |
cysG | ACS38189.1 | MexAM1_META1p3434 | MexAM1_META1p0227 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Transporter protein; Function of strongly homologous gene; transporter. | 0.400 |
cysG | amtB | MexAM1_META1p3434 | MexAM1_META1p2088 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Ammonium transport protein (Amt family); Function of strongly homologous gene; transporter. | 0.799 |
cysG | glnG-2 | MexAM1_META1p3434 | MexAM1_META1p3024 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator. | 0.694 |
cysG | mutM | MexAM1_META1p3434 | MexAM1_META1p4436 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.660 |
cysG | pnp | MexAM1_META1p3434 | MexAM1_META1p4416 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.660 |
fmdD | ACS41320.1 | MexAM1_META1p0979 | MexAM1_META1p3607 | Short-chain amide-urea binding porin; Function of strongly homologous gene; factor. | Putative branched-chain amino acid ABC transporter, substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter. | 0.901 |
fmdD | glnG-2 | MexAM1_META1p0979 | MexAM1_META1p3024 | Short-chain amide-urea binding porin; Function of strongly homologous gene; factor. | Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator. | 0.684 |
glnG-2 | ACS38189.1 | MexAM1_META1p3024 | MexAM1_META1p0227 | Two-component sigma-54 specific nitrogen transcriptional regulator, Fis subfamily; Function of strongly homologous gene; regulator. | Transporter protein; Function of strongly homologous gene; transporter. | 0.662 |