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moaD moaD moaE moaE moeB moeB moaC moaC moaA moaA thiG thiG ACS40459.1 ACS40459.1 gcvP gcvP ACS42727.1 ACS42727.1 ACS40798.1 ACS40798.1 ACS40796.1 ACS40796.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
moaDMolybdopterin converting factor, subunit 1; Function of strongly homologous gene; enzyme. (83 aa)    
Predicted Functional Partners:
moaE
Molybdopterin synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.998
moeB
Molybdopterin synthase sulfurylase; Function of strongly homologous gene; enzyme.
  
 0.979
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
  
 0.902
moaA
Molybdenum biosynthetic protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
  
 0.886
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
   
 
 0.787
ACS40459.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.769
gcvP
Glycine dehydrogenase / decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
    0.746
ACS42727.1
Putative molybdopterin biosynthesis-related protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.746
ACS40798.1
Putative molybdopterin biosynthesis-related protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.743
ACS40796.1
Putative molybdopterin biosynthesis-related protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
  
 0.715
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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