STRINGSTRING
phyR phyR nepR nepR ecfG1 ecfG1 ACS42595.1 ACS42595.1 ACS41250.1 ACS41250.1 ACS39808.1 ACS39808.1 rpoZ rpoZ ACS42239.1 ACS42239.1 ACS42579.1 ACS42579.1 ACS39475.1 ACS39475.1 ACS42202.1 ACS42202.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phyRPhyR; Key regulator for adaptation to epiphytic life (leaf colonizing) of the bacterium. Positively regulates several genes including katE, sodA, hsp20, dps and gloA. However, it is not known whether this regulation is direct or indirect. Also induces several dehydrogenases. (260 aa)    
Predicted Functional Partners:
nepR
Anti-sigma factor; Function experimentally demonstrated in the studied strain; factor.
   
 
 0.933
ecfG1
RNA polymerase sigma factor; Function experimentally demonstrated in the studied strain; factor.
 
  
 0.927
ACS42595.1
Putative hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.869
ACS41250.1
Putative histidine kinase of the HWE family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.859
ACS39808.1
Putative Histidine protein kinase of the HWE family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.852
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.841
ACS42239.1
Putative hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.841
ACS42579.1
Signal transduction histidine kinase; Function of strongly homologous gene; regulator.
 
   
 0.840
ACS39475.1
Hypothetical protein; No homology to any previously reported sequences.
  
 
 0.834
ACS42202.1
Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.832
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (26%) [HD]