node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40889.1 | ACS40890.1 | MexAM1_META1p3141 | MexAM1_META1p3142 | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Hypothetical protein; No homology to any previously reported sequences. | 0.489 |
ACS40889.1 | panB | MexAM1_META1p3141 | MexAM1_META1p1701 | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase, pantothenate biosynthetic process; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.928 |
ACS40889.1 | panC | MexAM1_META1p3141 | MexAM1_META1p2235 | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate-activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.928 |
ACS40889.1 | panE | MexAM1_META1p3141 | MexAM1_META1p2129 | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2-dehydropantoate 2-reductase (ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.926 |
ACS40889.1 | ribAB | MexAM1_META1p3141 | MexAM1_META1p3198 | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.451 |
ACS40890.1 | ACS40889.1 | MexAM1_META1p3142 | MexAM1_META1p3141 | Hypothetical protein; No homology to any previously reported sequences. | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.489 |
panB | ACS40889.1 | MexAM1_META1p1701 | MexAM1_META1p3141 | 3-methyl-2-oxobutanoate hydroxymethyltransferase, pantothenate biosynthetic process; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.928 |
panB | panC | MexAM1_META1p1701 | MexAM1_META1p2235 | 3-methyl-2-oxobutanoate hydroxymethyltransferase, pantothenate biosynthetic process; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate-activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.998 |
panB | panE | MexAM1_META1p1701 | MexAM1_META1p2129 | 3-methyl-2-oxobutanoate hydroxymethyltransferase, pantothenate biosynthetic process; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 2-dehydropantoate 2-reductase (ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.928 |
panB | ribAB | MexAM1_META1p1701 | MexAM1_META1p3198 | 3-methyl-2-oxobutanoate hydroxymethyltransferase, pantothenate biosynthetic process; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.539 |
panC | ACS40889.1 | MexAM1_META1p2235 | MexAM1_META1p3141 | Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate-activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.928 |
panC | panB | MexAM1_META1p2235 | MexAM1_META1p1701 | Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate-activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase, pantothenate biosynthetic process; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.998 |
panC | panE | MexAM1_META1p2235 | MexAM1_META1p2129 | Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate-activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 2-dehydropantoate 2-reductase (ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.928 |
panC | ribAB | MexAM1_META1p2235 | MexAM1_META1p3198 | Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate-activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.520 |
panE | ACS40889.1 | MexAM1_META1p2129 | MexAM1_META1p3141 | 2-dehydropantoate 2-reductase (ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.926 |
panE | panB | MexAM1_META1p2129 | MexAM1_META1p1701 | 2-dehydropantoate 2-reductase (ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoate hydroxymethyltransferase, pantothenate biosynthetic process; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.928 |
panE | panC | MexAM1_META1p2129 | MexAM1_META1p2235 | 2-dehydropantoate 2-reductase (ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantoate--beta-alanine ligase (Pantothenate synthetase) (Pantoate-activating enzyme); Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.928 |
panE | ribAB | MexAM1_META1p2129 | MexAM1_META1p3198 | 2-dehydropantoate 2-reductase (ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.451 |
ribAB | ACS40889.1 | MexAM1_META1p3198 | MexAM1_META1p3141 | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | Conserved hypothetical protein, putative domain: Ketopantoate reductase ApbA/PanE; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.451 |
ribAB | panB | MexAM1_META1p3198 | MexAM1_META1p1701 | 3,4-dihydroxy-2-butanone-4-phoshate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase, pantothenate biosynthetic process; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.539 |