node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39227.1 | cdd | MexAM1_META1p1365 | MexAM1_META1p3171 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.935 |
ACS39227.1 | deoA | MexAM1_META1p1365 | MexAM1_META1p3168 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.924 |
ACS39227.1 | surE | MexAM1_META1p1365 | MexAM1_META1p4626 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase surE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.919 |
ACS39227.1 | upp | MexAM1_META1p1365 | MexAM1_META1p1439 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.901 |
ACS39227.1 | xapA | MexAM1_META1p1365 | MexAM1_META1p3170 | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.910 |
ACS39498.1 | deoA | MexAM1_META1p1649 | MexAM1_META1p3168 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.926 |
ACS39498.1 | rutA | MexAM1_META1p1649 | MexAM1_META1p1664 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative luciferase family protein, putative flavin-dependent oxidoreductase; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | 0.900 |
ACS39498.1 | rutF | MexAM1_META1p1649 | MexAM1_META1p1660 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Flavin reductase domain protein, FMN-binding; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
ACS39498.1 | upp | MexAM1_META1p1649 | MexAM1_META1p1439 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.945 |
ACS39498.1 | xapA | MexAM1_META1p1649 | MexAM1_META1p3170 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.914 |
cdd | ACS39227.1 | MexAM1_META1p3171 | MexAM1_META1p1365 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | 0.935 |
cdd | deoA | MexAM1_META1p3171 | MexAM1_META1p3168 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.999 |
cdd | deoB | MexAM1_META1p3171 | MexAM1_META1p1808 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.576 |
cdd | deoC | MexAM1_META1p3171 | MexAM1_META1p3169 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 2-deoxyribose-5-phosphate aldolase, NAD(P)-linked; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. | 0.956 |
cdd | surE | MexAM1_META1p3171 | MexAM1_META1p4626 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 5'-nucleotidase surE (Nucleoside 5'-monophosphate phosphohydrolase); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.917 |
cdd | upp | MexAM1_META1p3171 | MexAM1_META1p1439 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.486 |
cdd | xapA | MexAM1_META1p3171 | MexAM1_META1p3170 | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.995 |
deoA | ACS39227.1 | MexAM1_META1p3168 | MexAM1_META1p1365 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative 5'-nucleotidase, 2'3'-cyclic-nucleotide 2'-phosphodiesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the 5'-nucleotidase family. | 0.924 |
deoA | ACS39498.1 | MexAM1_META1p3168 | MexAM1_META1p1649 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.926 |
deoA | cdd | MexAM1_META1p3168 | MexAM1_META1p3171 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Cytidine deaminase (cytidine aminohydrolase); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.999 |