node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS40922.1 | ACS41591.1 | MexAM1_META1p3175 | MexAM1_META1p3907 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.737 |
ACS40922.1 | ACS42193.1 | MexAM1_META1p3175 | MexAM1_META1p4563 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | Putative glycosyl transferase, putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.707 |
ACS40922.1 | ACS42730.1 | MexAM1_META1p3175 | MexAM1_META1p5126 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.717 |
ACS40922.1 | lpxA | MexAM1_META1p3175 | MexAM1_META1p5125 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.645 |
ACS40922.1 | lpxB | MexAM1_META1p3175 | MexAM1_META1p5127 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.637 |
ACS40922.1 | lpxC | MexAM1_META1p3175 | MexAM1_META1p3155 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.680 |
ACS40922.1 | lpxD | MexAM1_META1p3175 | MexAM1_META1p2065 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.665 |
ACS40922.1 | lpxK | MexAM1_META1p3175 | MexAM1_META1p3173 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.899 |
ACS40922.1 | lpxM | MexAM1_META1p3175 | MexAM1_META1p3702 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | Lipid A biosynthesis lauroyl acyltransferase; Function of strongly homologous gene; enzyme. | 0.580 |
ACS40922.1 | waaA | MexAM1_META1p3175 | MexAM1_META1p3174 | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.990 |
ACS41591.1 | ACS40922.1 | MexAM1_META1p3907 | MexAM1_META1p3175 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein, DUF374; Homologs of previously reported genes of unknown function. | 0.737 |
ACS41591.1 | ACS42193.1 | MexAM1_META1p3907 | MexAM1_META1p4563 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative glycosyl transferase, putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.694 |
ACS41591.1 | ACS42730.1 | MexAM1_META1p3907 | MexAM1_META1p5126 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.663 |
ACS41591.1 | lpxA | MexAM1_META1p3907 | MexAM1_META1p5125 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.601 |
ACS41591.1 | lpxB | MexAM1_META1p3907 | MexAM1_META1p5127 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.678 |
ACS41591.1 | lpxC | MexAM1_META1p3907 | MexAM1_META1p3155 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | UDP-3-O-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.648 |
ACS41591.1 | lpxD | MexAM1_META1p3907 | MexAM1_META1p2065 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.513 |
ACS41591.1 | lpxK | MexAM1_META1p3907 | MexAM1_META1p3173 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.740 |
ACS41591.1 | lpxM | MexAM1_META1p3907 | MexAM1_META1p3702 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Lipid A biosynthesis lauroyl acyltransferase; Function of strongly homologous gene; enzyme. | 0.754 |
ACS41591.1 | waaA | MexAM1_META1p3907 | MexAM1_META1p3174 | Putative permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.700 |