node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACS39498.1 | deoA | MexAM1_META1p1649 | MexAM1_META1p3168 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.926 |
ACS39498.1 | rutA | MexAM1_META1p1649 | MexAM1_META1p1664 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative luciferase family protein, putative flavin-dependent oxidoreductase; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | 0.900 |
ACS39498.1 | rutF | MexAM1_META1p1649 | MexAM1_META1p1660 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Flavin reductase domain protein, FMN-binding; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
ACS39498.1 | rutF-2 | MexAM1_META1p1649 | MexAM1_META1p3229 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | flavin:NADH oxidoreductase, putative alternative pyrimidine degradation enzyme; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
ACS39498.1 | upp | MexAM1_META1p1649 | MexAM1_META1p1439 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.945 |
ACS39498.1 | xapA | MexAM1_META1p1649 | MexAM1_META1p3170 | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.914 |
ACS40657.1 | glgX | MexAM1_META1p2904 | MexAM1_META1p1440 | Putative malto-oligosyltrehalose trehalohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycosyl hydrolase (Debranching enzyme); Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 13 family. | 0.932 |
ACS40657.1 | glgX-2 | MexAM1_META1p2904 | MexAM1_META1p3351 | Putative malto-oligosyltrehalose trehalohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycogen debranching enzyme; Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 13 family. | 0.899 |
ACS40657.1 | rutF | MexAM1_META1p2904 | MexAM1_META1p1660 | Putative malto-oligosyltrehalose trehalohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Flavin reductase domain protein, FMN-binding; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.665 |
ACS40657.1 | rutF-2 | MexAM1_META1p2904 | MexAM1_META1p3229 | Putative malto-oligosyltrehalose trehalohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | flavin:NADH oxidoreductase, putative alternative pyrimidine degradation enzyme; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.665 |
deoA | ACS39498.1 | MexAM1_META1p3168 | MexAM1_META1p1649 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative N-isopropylammelide isopropylaminohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.926 |
deoA | rutA | MexAM1_META1p3168 | MexAM1_META1p1664 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Putative luciferase family protein, putative flavin-dependent oxidoreductase; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | 0.900 |
deoA | rutF | MexAM1_META1p3168 | MexAM1_META1p1660 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Flavin reductase domain protein, FMN-binding; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
deoA | rutF-2 | MexAM1_META1p3168 | MexAM1_META1p3229 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | flavin:NADH oxidoreductase, putative alternative pyrimidine degradation enzyme; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.900 |
deoA | upp | MexAM1_META1p3168 | MexAM1_META1p1439 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.956 |
deoA | xapA | MexAM1_META1p3168 | MexAM1_META1p3170 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.991 |
glgX | ACS40657.1 | MexAM1_META1p1440 | MexAM1_META1p2904 | Glycosyl hydrolase (Debranching enzyme); Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 13 family. | Putative malto-oligosyltrehalose trehalohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.932 |
glgX | glgX-2 | MexAM1_META1p1440 | MexAM1_META1p3351 | Glycosyl hydrolase (Debranching enzyme); Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 13 family. | Glycogen debranching enzyme; Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 13 family. | 0.908 |
glgX | rutF | MexAM1_META1p1440 | MexAM1_META1p1660 | Glycosyl hydrolase (Debranching enzyme); Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 13 family. | Flavin reductase domain protein, FMN-binding; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.666 |
glgX | rutF-2 | MexAM1_META1p1440 | MexAM1_META1p3229 | Glycosyl hydrolase (Debranching enzyme); Function of strongly homologous gene; enzyme; Belongs to the glycosyl hydrolase 13 family. | flavin:NADH oxidoreductase, putative alternative pyrimidine degradation enzyme; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway; Belongs to the non-flavoprotein flavin reductase family. RutF subfamily. | 0.666 |