ACS41024.1 protein (Methylorubrum extorquens)

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Score

ACS41024.1

Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (280 aa)

Predicted Functional Partners:

tgt

0.791

queA

0.773

ACS41022.1

0.549

ACS39480.1

0.438

ACS41021.1

0.423

Your Current Organism:

Methylorubrum extorquens

NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACS39480.1	ACS41024.1	MexAM1_META1p1628	MexAM1_META1p3284	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.438
ACS41021.1	ACS41022.1	MexAM1_META1p3281	MexAM1_META1p3282	Hypothetical protein; No homology to any previously reported sequences.	Putative Monooxygenase, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.581
ACS41021.1	ACS41024.1	MexAM1_META1p3281	MexAM1_META1p3284	Hypothetical protein; No homology to any previously reported sequences.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.423
ACS41021.1	queA	MexAM1_META1p3281	MexAM1_META1p3283	Hypothetical protein; No homology to any previously reported sequences.	S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	0.484
ACS41021.1	tgt	MexAM1_META1p3281	MexAM1_META1p3285	Hypothetical protein; No homology to any previously reported sequences.	Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...]	0.484
ACS41022.1	ACS41021.1	MexAM1_META1p3282	MexAM1_META1p3281	Putative Monooxygenase, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Hypothetical protein; No homology to any previously reported sequences.	0.581
ACS41022.1	ACS41024.1	MexAM1_META1p3282	MexAM1_META1p3284	Putative Monooxygenase, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.549
ACS41022.1	queA	MexAM1_META1p3282	MexAM1_META1p3283	Putative Monooxygenase, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	0.561
ACS41022.1	tgt	MexAM1_META1p3282	MexAM1_META1p3285	Putative Monooxygenase, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...]	0.547
ACS41024.1	ACS39480.1	MexAM1_META1p3284	MexAM1_META1p1628	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.438
ACS41024.1	ACS41021.1	MexAM1_META1p3284	MexAM1_META1p3281	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Hypothetical protein; No homology to any previously reported sequences.	0.423
ACS41024.1	ACS41022.1	MexAM1_META1p3284	MexAM1_META1p3282	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Putative Monooxygenase, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.549
ACS41024.1	queA	MexAM1_META1p3284	MexAM1_META1p3283	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	0.773
ACS41024.1	tgt	MexAM1_META1p3284	MexAM1_META1p3285	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...]	0.791
queA	ACS41021.1	MexAM1_META1p3283	MexAM1_META1p3281	S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	Hypothetical protein; No homology to any previously reported sequences.	0.484
queA	ACS41022.1	MexAM1_META1p3283	MexAM1_META1p3282	S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	Putative Monooxygenase, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.561
queA	ACS41024.1	MexAM1_META1p3283	MexAM1_META1p3284	S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.773
queA	tgt	MexAM1_META1p3283	MexAM1_META1p3285	S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein queA); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).	Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...]	0.998
tgt	ACS41021.1	MexAM1_META1p3285	MexAM1_META1p3281	Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...]	Hypothetical protein; No homology to any previously reported sequences.	0.484
tgt	ACS41022.1	MexAM1_META1p3285	MexAM1_META1p3282	Queuine tRNA-ribosyltransferase (tRNA-guanine transglycosylase) (Guanine insertion enzyme); Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowi [...]	Putative Monooxygenase, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.547