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hppa hppa hemE hemE trmU trmU rppH rppH ppk ppk ACS42857.1 ACS42857.1 phoU phoU metF metF pitA pitA ppnK ppnK phoB phoB
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Predicted Interactions
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gene fusions
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textmining
co-expression
protein homology
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hppaH+ translocating pyrophosphate synthase; Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force. (710 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
      
 0.730
trmU
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
     
 0.727
rppH
(di)nucleoside polyphosphate hydrolase (Nudix family); Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
     
 0.662
ppk
Polyphosphate kinase, component of RNA degradosome; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
      
 0.661
ACS42857.1
Serine protease; Function of strongly homologous gene; enzyme.
      
 0.661
phoU
Negative regulator of PhoR/PhoB two-component regulator; Plays a role in the regulation of phosphate uptake.
      
 0.660
metF
5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.535
pitA
Low-affinity phosphate transport protein (PiT family); Function of strongly homologous gene; transporter.
     
 0.508
ppnK
Putative inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
      
 0.449
phoB
Phosphate regulon transcriptional regulatory protein PhoB; Function of homologous gene experimentally demonstrated in an other organism; regulator.
      
 0.402
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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