STRINGSTRING
ispB ispB uppS uppS uppS-2 uppS-2 ispA ispA crtE crtE ubiA ubiA crtB crtB ACS42247.1 ACS42247.1 ACS38761.1 ACS38761.1 xseB xseB hemC hemC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ispBOctaprenyl diphosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family. (340 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.956
uppS-2
Undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
 
 
 0.949
ispA
Geranyltranstransferase (farnesyl-diphosphate synthase); Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
  
  
0.925
crtE
Geranylgeranyl pyrophosphate synthase; Function of strongly homologous gene; enzyme; Belongs to the FPP/GGPP synthase family.
  
  
0.917
ubiA
P-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
 
 0.913
crtB
Phytoene synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.898
ACS42247.1
Terpenoid synthase, putative phytoene synthase; Function of strongly homologous gene; enzyme.
  
 0.882
ACS38761.1
Putative hydrolase, metallo-beta-lactamase superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.785
xseB
Exodeoxyribonuclease VII small subunit (exonuclease VII small subunit); Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
  
 0.642
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.567
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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