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guaD-2 guaD-2 guaD guaD apt apt xapA xapA hpt hpt Oxidoreductase Oxidoreductase Oxidoreductase-2 Oxidoreductase-2 ACS41607.1 ACS41607.1 ACS38532.1 ACS38532.1 ACS38534.1 ACS38534.1 ACS40762.1 ACS40762.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
guaD-2Guanine deaminase (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH) (GDEase); Function of strongly homologous gene; enzyme. (153 aa)    
Predicted Functional Partners:
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
    
 0.915
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
  0.909
xapA
Xanthosine phosphorylase (purine nucleoside phosphorylase); The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.909
hpt
Hypoxanthine phosphoribosyl transferase; Function of strongly homologous gene; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.908
Oxidoreductase
Oxidoreductase, FAD-binding subunit; Function of strongly homologous gene; enzyme.
    
 0.904
Oxidoreductase-2
Oxidoreductase, FAD-binding subunit; Function of strongly homologous gene; enzyme.
    
 0.904
ACS41607.1
Oxidoreductase, FAD-binding subunit; Function of strongly homologous gene; enzyme.
    
 0.904
ACS38532.1
Oxidoreductase, 2Fe-2S subunit; Function of strongly homologous gene; enzyme.
    
  0.901
ACS38534.1
Oxidoreductase, molybdopterin-binding subunit; Function of strongly homologous gene; enzyme.
    
 0.901
ACS40762.1
Oxidoreductase, 2Fe-2S subunit; Function of strongly homologous gene; enzyme.
    
  0.901
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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