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trmJ trmJ rrmJ rrmJ cysS cysS rnhB rnhB pncA pncA fae-3 fae-3 ACS38419.1 ACS38419.1 truB truB ACS38757.1 ACS38757.1 aroB aroB rsmB rsmB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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trmJtRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (245 aa)    
Predicted Functional Partners:
rrmJ
Ribosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
  
   
 0.731
cysS
Cysteine tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
      0.672
rnhB
RNAse HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.617
pncA
Nicotinamidase; Function of strongly homologous gene; enzyme.
 
      0.598
fae-3
Formaldehyde activating enzyme-like protein; Function of strongly homologous gene; putative enzyme.
       0.574
ACS38419.1
Putative chorismate mutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
  
 0.513
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
   
 0.478
ACS38757.1
Putative Lipoprotein releasing system, transmembrane protein, LolC/E family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
    0.462
aroB
Bifunctional shikimate kinase (N-terminal) / dehydroquinate synthase (C-terminal) enzyme; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
   
    0.424
rsmB
16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent; Function of strongly homologous gene; enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
   
 0.423
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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