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ACS41120.1 ACS41120.1 iscS iscS hmp hmp hmp-2 hmp-2 ACS40052.1 ACS40052.1 ribD ribD nrdR nrdR ribE-2 ribE-2 ACS39680.1 ACS39680.1 glyA glyA ACS38645.1 ACS38645.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ACS41120.1Putative transcriptional regulator, Rrf2 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (150 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent; Function of strongly homologous gene; enzyme.
  
  
 0.789
hmp
Bifunctional: nitric oxide dioxygenase (N-terminal); Function of strongly homologous gene; enzyme; Belongs to the globin family.
 
   
 0.636
hmp-2
Bifunctional: nitric oxide dioxygenase (N-terminal); Function of strongly homologous gene; enzyme; Belongs to the globin family.
 
   
 0.630
ACS40052.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.581
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.570
nrdR
Transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
     
 0.536
ribE-2
Riboflavin synthase, alpha subunit; Function of strongly homologous gene; enzyme.
       0.528
ACS39680.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
  
 0.435
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.421
ACS38645.1
DnaJ-like protein; Function of strongly homologous gene; factor.
  
  
 0.404
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
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