STRINGSTRING
relA relA ACS41373.1 ACS41373.1 ACS39852.1 ACS39852.1 gmk gmk mazG mazG pyk pyk pyk-2 pyk-2 ACS42836.1 ACS42836.1 nrd nrd ACS38374.1 ACS38374.1 ACS38794.1 ACS38794.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
relAGTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (743 aa)    
Predicted Functional Partners:
ACS41373.1
Exopolyphosphatase; Function of strongly homologous gene; enzyme.
 
 
 0.939
ACS39852.1
Exopolyphosphatase; Function of strongly homologous gene; enzyme.
 
 
 0.936
gmk
Guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP.
  
 
 0.929
mazG
Nucleoside triphosphate pyrophosphohydrolase MazG; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.927
pyk
Pyruvate kinase; Function of strongly homologous gene; enzyme; Belongs to the pyruvate kinase family.
  
 
 0.920
pyk-2
Pyruvate kinase; Function of strongly homologous gene; enzyme.
  
 
 0.920
ACS42836.1
Putative transmembrane adenylate/guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
  0.912
nrd
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent, large subunit; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
 0.901
ACS38374.1
Putative Adenylate/Guanylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
  0.900
ACS38794.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
     
  0.900
Your Current Organism:
Methylorubrum extorquens
NCBI taxonomy Id: 272630
Other names: M. extorquens AM1, Methylobacterium extorquens AM1, Methylorubrum extorquens AM1, Pseudomonas sp. AM1
Server load: low (16%) [HD]